Journal: Frontiers in Cellular and Infection Microbiology
Article Title: Combination With Tomatidine Improves the Potency of Posaconazole Against Trypanosoma cruzi
doi: 10.3389/fcimb.2021.617917
Figure Lengend Snippet: Sum of the mean fractional inhibitory concentration indices (ΣFICI) of the combinations between Ro48-8071 or tomatidine hydrochloride and benznidazole, posaconazole, or fexinidazole in different fixed ratio proportions (1:3, 1:1, and 3:1; the first number corresponds to the standard drug) against T. cruzi intracellular amastigotes (strain Tulahuen in L6 cell lines).
Article Snippet: Amitryptiline (hydrochloride), FTY720, FTY720 phosphate, AMP-deoxynojirimicin, D609 (potassium salt), fumonisin B1, myriocin, Ro48-8071, TMP-153, GW4869 (hydrochloride hydrate), PDMP (hydrochloride), tomatidine hydrochloride (TH) were purchased from Cayman chemicals and bezafibrate, quinuclidine hydrochloride, 3-aminoquinuclidine dihydrochloride, and posaconazole (Posa) were from Sigma-Aldrich Switzerland.
Techniques: Concentration Assay